Protein-protein and protein-salt interactions in aqueous protein solutions containing concentrated electrolytes
نویسندگان
چکیده
منابع مشابه
Protein-Protein Interactions in Salt Solutions
Protein-protein interactions drive many biophysical processes of proteins in solutions, such as aggregation, solubility, and phase transitions including crystallization, gelation, and amorphous precipitation. Many of these processes are of significant research interest because of their practical importance. In the biopharmaceutical industry, it is crucial to prevent therapeutic proteins from ag...
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Background: Protein-protein interactions do not provide any direct information regarding the domains within the proteins that mediate the interactions. The majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. Most of the former studies focus only on interacting domain pairs. However they do not consider the in...
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We report the four diffusion coefficients for the lysozyme-MgCl2-water ternary system at 25 degrees C and pH 4.5. The comparison with previous results for the lysozyme-NaCl-water ternary system is used to examine the effect of salt stoichiometry on the transport properties of lysozyme-salt aqueous mixtures. We find that the two cross-diffusion coefficients are very sensitive to salt stoichiomet...
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Protein-protein interactions were investigated for α-chymotrypsinogen by static and dynamic light scattering (SLS and DLS, respectively), as well as small-angle neutron scattering (SANS), as a function of protein and salt concentration at acidic conditions. Net protein-protein interactions were probed via the Kirkwood-Buff integral G22 and the static structure factor S(q) from SLS and SANS data...
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Animal agricultural production systems are major sources of nonpoint pollution affecting quality of water sources. Nitrogen has been identified as the foremost source of nonpoint water pollution and the potential negative impacts of N have become an area of public concern. protein degradation from feed ingredients is an important factorinfluencing AA supply to the duodenum. Ruminal proteolysis...
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ژورنال
عنوان ژورنال: Biotechnology and Bioengineering
سال: 1998
ISSN: 0006-3592,1097-0290
DOI: 10.1002/(sici)1097-0290(19980520)58:4<451::aid-bit13>3.0.co;2-e